Medically reviewed by Dena Westphalen, Pharm.D. — created by Jessica Caporuscio, Pharm.D. — updated on November 8, 2020

People take alprazolam (Xanax) come treat anxiety and panic disorders. Acquisition Xanax can reason mild-to-serious side effects. Taking too lot Xanax or taking various other drugs alongside Xanax can increase the hazard of overdose.

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Xanax belongs to a class of medications referred to as benzodiazepines. Together with its usage for anxiety, some human being use Xanax because that sleeplessness, premenstrual disorder, and depression. However, the Food and also Drug management (FDA) have actually not at this time approved the medicine for these uses.

Some human being have supplied Xanax for recreational functions or in ~ dosages greater than their doctor prescribed. When world use medicine without a prescription or at various dosages, there is an raised risk of medicine misuse and possible overdose.

This write-up will talk about the symptoms, treatments, and risk factors connected with Xanax overdose. The will likewise explain what to perform if someone has taken too lot Xanax.

What wake up if friend take also much?

Share ~ above PinterestDrowsiness is one possible side impact of taking too much Xanax.
Doctors will frequently prescribe Xanax dosages of around 0.25 to 0.5 milligrams (mg) 3 times per day. Some people may require a dosage of as much as 4 mg per day. For panic disorder, part doctors might prescribe dosage of approximately 10 mg per day.

Older adults and also people with progressed liver failure may require lower dosages the Xanax, together their bodies can be more sensitive to the impacts of benzodiazepines.

Doctors aim to prescribe the lowest efficient dosage because that the shortest term to manage the danger of dependence.

People that take too much Xanax might experience:

drowsinesspoor coordinationblurred visionconfusion

Sometimes, people may endure delayed symptoms, if others may experience major symptoms, such as coma or also death.

Mixing Xanax with other medications, alcohol, or both can cause overdose. Sometimes, overdose is unintentional, but some world may use Xanax alone or with various other substances come intentionally damage themselves.

Xanax is a common drug and also has a high likelihood that misuse. Researchers imply that Xanax is the most common benzodiazepine involved in emergency room visits concerned the misuse that drugs.


If someone overdoses top top Xanax, they might experience mild-to-severe side effects. Also if a human being experiences mild next effects, lock still require emergency clinical attention.

Symptoms that Xanax overdose might include:

drowsinessconfusionimpaired coordinationreduced reflexescomadeath

People who overdose ~ above Xanax alone may experience mild drowsiness v normal or near normal vital signs. A benzodiazepine overdose may likewise lead come slurred speech and also an changed mental state.

People that experience an obstacle breathing after taking too much Xanax have likely bring away the drug v other main nervous device (CNS) depressants or alcohol. Respiratory difficulties are uncommon in diverted Xanax overdoses.

Doctors have actually not figured out the precise dosage the Xanax the can reason breathing problems due to the fact that it deserve to depend on number of factors, including:

how much of the medicine the human being tooktheir drug tolerancetheir weighttheir ageany other substances they take it at the very same timetheir genetics

Severe complications regarded benzodiazepine overdose deserve to include:

respiratory arrestdeath

If someone is experiencing overdose side effects, they or someone else should speak to their regional emergency number immediately.

Sometimes, overdose is unintentional. If a person has actually been acquisition benzodiazepines with alcohol or various other sedating medications, they may not know that they have actually overdosed top top the drug.

Individuals have to tell your doctor and pharmacist which medicines they are taking so the the healthcare experts can decision whether or no Xanax is appropriate and safe because that them.

Doctors warn the mixing benzodiazepines and also opioids, alcohol, or various other CNS depressants can cause drowsiness, breathing problems, coma, or also death.


Both opioids and benzodiazepines can affect breathing since they plot on GABA and mu receptors, which room receptors in the mind that manage breathing.

Taking both of this drugs at the very same time deserve to increase the threat of serious sedation, breath problems, coma, and death. A human being should never ever use Xanax with opioids or take more than the prescribed dosage, unless a doctor recommends it.

Doctors must prescribe the lowest possible dosage for the shortest feasible duration.


Taking benzodiazepines such as Xanax has actually a depressant effect. Alcohol has actually a comparable effect. Therefore, human being should stop using alcohol v Xanax, together this can lead to adverse, and possibly life threatening, effects.

People should inform their doctor around their alcohol consumption habits before using Xanax.

Other CNS depressants

People who integrate CNS depressants with Xanax may experience one increased activity of the benzodiazepine. The additive side impacts from different drugs can cause CNS depression, consisting of symptoms such as sedation and also drowsiness.

CNS depressants include:

psychotropic drugsanticonvulsantsantihistaminesalcohol


Doctors indicate that adults over 65 years old may experience digoxin toxicity if they combine digoxin with Xanax.

If a human being needs to take it both of these medications, doctors must monitor them closely for digoxin toxicity, i m sorry may incorporate the complying with symptoms:

visual disturbances, such as yellow or eco-friendly discolorationan rarely often rare heartbeatshortness of breathfainting or pass outdizziness

Cytochrome P450 3A

The enzyme cytochrome P450 3A (CYP450 3A) digests Xanax in the liver. Drugs that block the work of this enzyme will affect how the body gets rid of Xanax, which can increase its levels in the blood.

Some instances of drugs that block the result of CYP450 3A encompass fluoxetine and also birth regulate pills.

If a human does not recognize if they are using a drug that block CYP450 3A, they should talk to their physician before starting Xanax.

If someone has overdosed top top Xanax, it is an essential to speak to the Poison regulate helpline in ~ 800-222-1222. Info is also obtainable on the Poison control website.

The doctors, nurses, and also pharmacists who work-related for Poison regulate offer free, confidential consultations 24 hours per day and 7 days every week. They can assist civilization who may have overdosed.

If someone has actually collapsed, had actually a seizure, has an obstacle breathing, or will not wake up up, someone must speak to 911. The person will must go come the closestly emergency room ideal away.

Sometimes, a human may not endure the impact of the overdose or misuse immediately. Others might not be mindful that they have overdosed on Xanax if they space unintentionally combine the drug with various other substances, including alcohol.

Lower dosages can cause toxicities in enlarge adults.

Doctors treat Xanax and also other benzodiazepine overdoses with supportive care, relying on the person’s symptoms. This may encompass monitoring their an important signs, providing them intravenous fluids, and, if they have actually severe breathing problems, using a breathing tube.

Doctors execute not use activated charcoal, dialysis, or bowel watering for benzodiazepine toxicity.

Flumazenil injections

Doctors might give world with severe benzodiazepine toxicity a flumazenil injection come treat the overdose. Flumazenil is an injectable medicine that reverses the effect of a benzodiazepine by blocking the benzodiazepine receptor.

A doctor may provide adults flumazenil injections if they have overdosed top top benzodiazepines. Castle can additionally give children aged 1–17 years flumazenil to reverse the impacts of benzodiazepines after ~ a surgical procedure.

Usually, however, the dangers of using flumazenil outweigh the feasible benefits, so doctors perform not recommend it routinely.

A significant side effect of flumazenil is seizures, and the drug carries a black box warning come this effect. This type of warning is the many serious warning the the FDA give to drugs.

When medical professionals give world flumazenil, they need to be all set to treat and manage any type of seizures the occur.

People that overdose top top Xanax alone may have mild symptoms of toxicity. However, when people combine Xanax with various other drugs that influence the CNS, they might experience much more severe symptoms, including an obstacle breathing, coma, and possibly death.

People acquisition Xanax should let your doctors and also pharmacists recognize if they are additionally taking various other medications. CNS depressants, digoxin, opioids, and CYP450 3A inhibitors can all interact with Xanax and also cause unintentional overdose.

Some people try to injury themselves by taking large amounts of Xanax or combining Xanax with other drugs. Overdoses and misuse the Xanax have the right to lead come coma and also death.

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If someone has overdosed top top Xanax, it is vital to gain emergency medical help immediately.